The Ben Berman lab at Hebrew University

This is the website of the Ben Berman lab at The Hebrew University of Jerusalem. Our goal is to understand the genomic patterns of DNA methylation and other epigenetic markers that underlie gene regulation in human development, aging, and disease. Genomic epigenetic signatures occur across a wide range of genomic scales, and our lab develops computational algorithms and software packages to address this challenge. We also investigate these signatures as clincally-relevant biomarkers. See our Research page for more details.

Shown to the left are examples of multi-scale mapping of DNA methylation: (1) Allele-specific methylation across a 70 base pair (bp) region encompassing the H19 imprinting control element, (2) phased methylation pattern representing regularly-spaced nucleosomes in 2,000 bp regions centered on a transcription factor binding site CTCF (middle), and (3) decreased methylation within long domains within a 30 million bp chromosome arm (bottom).

If you are interested in joining us as an MSc, PhD student or postdoctoral researcher, please see our Job openings page. We are always looking for talented new scientists